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سرپرست زیست فرآیند

  • نام و نام خانوادگی: سعید عباسعلیزاده

  • پست سازمانی: سرپرست زیست فرآیند

  • آدرس ایمیل:


مهندس سعید عباسعلیزاده در سال 1382 مدرک کارشناسی خود را از دانشگاه آزاد و در سال 1385 مدرک کارشناسی ارشد خود را در رشته مهندسی علوم وصنایع غذایی گرایش بیوتکنولوژی از دانشگاه تبریز دریافت نمود. وی در سال 1388 به پژوهشگاه رویان پیوست و از سال 1393 دوره دکتری خود را در رشته مهندسی زیستی گرایش سلول درمانی و پزشکی بازساختی در دانشگاه لیسبون به صورت مشترک با پژوهشگاه رویان و دانشگاه MIT آغاز نموده است. زمینه‌های تحقیقاتی او شامل توسعه زیست فرآیند تولید محصولات بیولوژیک و پزشکی بازساختی تحت شرایط GMP است. حاصل پژوهش‌های وی در بیش از 20 مقاله در مجلات معتبر بین‌المللی به چاپ رسیده است و تاکنون دوبار به عنوان پژوهشگر برتر پژوهشکده بیوتکنولوژی کشاورزی و یک بار به عنوان پژوهشگر برتر پژوهشگاه رویان در سال 1397 انتخاب گردیده است.

Abbasalizadeh S, Larijani MR, Baharvand H (2010). “Large scale expansion of human pluripotent stem cells for cell therapy applications” Iranian Journal of Epidemiology, 8 (3-4). (In Persian)

Abbasalizadeh S, Larijani MR, Samadian A, Baharvand H (2012). Bioprocess Development for Mass Production of Size-Controlled Human Pluripotent Stem Cell Aggregates in Stirred Suspension Bioreactor. Tissue Engineering Part C: Methods, 18:831-51.

Abbasalizadeh, S. and H. Baharvand (2013). “Technological progress and challenges towards cGMP manufacturing of human pluripotent stem cells based therapeutic products for allogeneic and autologous cell therapies” Biotechnology advances, 31(8): 1600-1623.

– H. Fonoudi, H. Ansari, S. Abbasalizadeh, MR. Larijani, S. Kiani, S. Hashemizadeh, A. Sharifi Zarchi, A. Bosman, G. M. Blue, S. Pahlavan, M. Perry, Y. Orr, Y. Mayorchak, J. Vandenberg, M. Talkhabi, D. Winlaw, R. P. Harvey, N. Aghdami, H. Baharvand, (2015), A universal and Robust Integrated Platform for the Scalable Production of Human Cardiomyocytes from Pluripotent Stem Cells, Stem cells and translational medicine, 4(12):1482-94.

– Fonoudi, H., Ansari, H., Abbasalizadeh, S., Blue, G. M., Aghdami, N., Winlaw, D. S., et al. (2016). Large-Scale Production of Cardiomyocytes from Human Pluripotent Stem Cells Using a Highly Reproducible Small Molecule-Based Differentiation Protocol. J. Vis. Exp, (113), e54276.

– Nemati S, Abbasalizadeh S, Baharvand H (2016). Scalable Expansion of Human Pluripotent Stem Cell-Derived Neural Progenitors in Stirred Suspension Bioreactor Under Xeno-free Condition. Methods Mol Biol, 1502:143-58.

– Mohammadi, P., Kass youssef, K., Aghdami, N., Abbasalizadeh, S., & Baharvand, H. (2016). Human Hair Reconstruction: Close but Yet So Far. Stem Cells and Development, 25(23):1767-1779.

Abbasalizadeh S, Pakzad M, Cabral JM, Baharvand H (2017). Allogeneic cell therapy manufacturing: process development technologies and facility design options. Expert Opinion on Biological Therapy, 17(10):1201-19.

– Rajabi S, Pahlavan S, Kazemi Ashtiani M, Ansari H, Abbasalizadeh S, Azam Sayahpour F, Varzideh F, Kostin S, Aghdami N, Braun T, Baharvand H, (2017). Human embryonic stem cell-derived cardiovascular progenitor cells efficiently colonize in bFGF-tethered natural matrix to construct contracting humanized rat hearts. Biomaterials, 154: 99-112.

– Namiri, M., M. Kazemi Ashtiani, S. Abbasalizadeh, Z. Mazidi, E. Mahmoudi, S. Nikeghbalian, N. Aghdami and H. Baharvand (2017). “Improving the biological function of decellularized heart valves through integration of protein tethering and three‐dimensional cell seeding in a bioreactor.” Journal of tissue engineering and regenerative medicine.

– Farzaneh Z, Najarasl M, Abbasalizadeh S, Vosough M, and Baharvand H (2018). Developing a Cost-Effective and Scalable Production of Human Hepatic Competent Endoderm from Size-Controlled Pluripotent Stem Cell Aggregates. Stem Cells and Development (ja).

– Mohammadipour, M., M. Mousivand, G. Salehi Jouzani and S. Abbasalizadeh (2009). “Molecular and biochemical characterization of Iranian surfactin-producing Bacillus subtilis isolates and evaluation of their biocontrol potential against Aspergillus flavus and Colletotrichum gloeosporioides.” Canadian journal of microbiology, 55(4): 395-404.

– Salehi Jouzani Gholamreza, Matin Mohamadipour, Maryam Mousivand, S. Abbasalizadeh, Mohammad Salari, Naser Panjehkeh, (2009), Molecular and biochemical characterization of Iranian surfactin producing Bacillus subtilis isolates Bulletin of International Organization for Biological and Integrated Control of Noxious Animals and Plants, IOBC/WPRS Bulletin, Vol. 43, 62-66.

– Askari, N., Gh. Salehi Jouzani1, M. Mousivand1 A. Foroutan, A. Hagh Nazari, S. Abbasalizadeh, S. Soheilivand, and M. Mardi (2011). Evaluation of Anti-Phytoplasma Properties of Surfactin and Tetracycline Towards Lime Witches’ Broom Disease Using Real-Time PCR. J. Microbiol. Biotechnol., 21(1): 81–88.

– Juibari, M. M., S. Abbasalizadeh, G. S. Jouzani and M. Noruzi (2011). “Intensified biosynthesis of silver nanoparticles using a native extremophilic Ureibacillus thermosphaericus strain.” Materials Letters, 65(6): 1014-1017.

Abbasalizadeh, S., G. S. Jouzani, et al. (2012). “Draft Genome Sequence of Ureibacillus thermosphaericus Strain Thermo-BF, isolated from Ramsar Hot Springs in Iran.” Journal of Bacteriology, 194(16): 4431-4431.

– Mood, S. H., A. H. Golfeshan, M. Tabatabaei, S. Abbasalizadeh and M. Ardjmand (2013). “Comparison of different ionic liquids pretreatment for barley straw enzymatic saccharification.” 3 Biotech, 3(5): 399-406.

– Mood, S. H., A. H. Golfeshan, M. Tabatabaei, S. Abbasalizadeh, M. Ardjmand and G. S. Jouzani (2014). “Comparison of different ionic liquids pretreatment for Corn Stover enzymatic saccharification.” Preparative Biochemistry and Biotechnology, 4; 44(5):451-63.

– O. Zahed, G. Salehi Jouzani, S. Abbasalizadeh, F. Khodaiyan, M. Tabatabaei, (2015). Continuous co-production of ethanol and xylitol from rice straw hydrolysate in a membrane bioreactor. Folia Microbiol (Praha), 61(3):179-89.

Saeed Abbasalizadeh, Mohammad Amin Hejazi, Mahdi Pesaran Hajiabbas. Kinetics of β-galactosidase Production by Lactobacillus bulgaricus During pH Controlled Batch Fermentation in Three Commercial Bulk Starter Media (2015). Applied Food Biotechnology, 2(4): 39-47

– G. Salehi Jouzani; S. Abbasalizadeh; M. Mohammad Fata; H. Morsali, (2015), Development of a Cost Effective Bioprocess for Production of an Iranian Anti-Coleoptera Bacillus thuringiensis Strain Journal of Agricultural Science and Technology,17: 1183-1196.

– M. Motamedi Juibari, L. Parsa Yeganeh, Saeed Abbasalizadeh, R. Azarbaijani, SH. Mousavi, M. Tabatabaei, G. Salehi Jouzani, G. Hosseini Salekdeh, (2015) Investigation of a Hot-Spring Extremophilic Ureibacillus thermosphaericus Strain Thermo-BF for Extracellular Biosynthesis of Functionalized Gold Nanoparticles, 5 (4): 233–241.